Project Description
My research focuses on model-based and model-free control on process intensification especially on continuous crystallization, filtration, and drying system for pharmaceutical manufacturing. I am interested in designing a robust process system for desired product attributes from model-based optimization and developing a controller to follow a set of dynamic perfomance trajectories efficiently and reliably.
Publications
- Destro, F., Hur, I., Wang, V., Abdi, M., Feng, X., Wood, E., Coleman, S., Firth, P., Barton, A., Barolo, M., & Nagy, Z. K. (2021). Mathematical modeling and digital design of an intensified filtration-washing-drying unit for pharmaceutical continuous manufacturing. Chemical Engineering Science, 244, 116803. https://doi.org/10.1016/j.ces.2021.116803
Conference Presentations
- F. Destro, I. Hur, D. Casas-Orozco, S. Lee, M. Abdi, X. Feng, E. Wood, M. Barolo, and Z. K. Nagy. “Digital design of an intensified filtration-drying unit for pharmaceutical upstream manufacturing”, 2020 AIChE Annual Meeting, San Francisco, CA. Session Integrated Design for Drug Substance Processes.
Education
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